Publications

The mGluR theory of Fragile X mental retardation
M.F. Bear, K. M. Huber and S.T. Warren, 2004 July. Trends in Neuroscience; 27(7): 370-377

Therapeutic implications of the mGluR theory of Fragile X mental retardation
M.F. Bear, 2005 August. Genes, Brain and Behavior; 4(6):393-8

Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP
Q.J. Yan, M. Rammal, M. Tranfaglia and R.P. Bauchwitz, 2005 Dec. Neuropharmacology; 49(7):1053-66

Altered synaptic plasticity in a mouse model of Fragile X mental retardation
K. M. Huber, S.M. Gallagher, S.T. Warren and M.F. Bear, 2002 May. Proceedings of the National Academy of Sciences of the United States of America; 99(11):7746-50

Deletion of FMR1 in Purkinje Cells Enhances Parallel Fiber LTD , Enlarges Spines, and Attenuates Cerebellar Eyelid Conditioning in Fragile X Syndrome
S.K.E. Koekkoek, K. Yamaguchi, B.A. Milojkovic, B.R. Dortland, T.J.H. Ruigrok, R. Maex, W. De Graaf, A.E. Smit, F. VanderWerf, C.E. Bakker, R. Willemsen, T. Ikeda, S. Kakizawa, K. Onodera, D.L. Nelson, E. Mientjes, M. Joosten, E. De Schutter, B.A. Oostra, M. Ito and C.I. De Zeeuw, 2005 Aug. Neuron; 47(3):339-52

Pharmacological Rescue of Synaptic Plasticity, Courtship Behavior, and Mushroom Body Defects in a Drosophila Model of Fragile X Syndrome
S.M.J. McBride, C.H. Choi, Y. Wang, D. Liebelt, E. Braunstein, D. Ferreiro, A. Sehgal, K.K. Siwicki, T.C. Dockendorff, H.T. Nguyen, T.V. McDonald and T.A. Jongens, 2005 Mar. Neuron; 45(5):753-64

Courting a Cure for Fragile X
G.Dolen and M.F. Bear, 2005 Mar. Neuron. 45(5): 642-644

The Autistic Neuron: Troubled Translation?
R.J. Kelleher and M.F.Bear, 2008 Oct. Cell. 135(3): 401-6

Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of Fragile X Syndrome
G. Dolen and M.F. Bear, 2008 Mar. Journal of Physiology 586(6): 1503-1508

Correction of Fragile X Syndrome in Mice
G. Dolen, E. Osterweil, B.S. Rao, G.B. Smith, B.D. Auerbach, S. Chattarji and M.F. Bear, 2007 Dec. Neuron; 56(6) 955-962

Fragile X: Translation in Action
M.F. Bear, G. Dolen, E. Osterweil and N. Nagarajan, 2008 Jan. Neuropsychopharmacology; 33(1): 84-87

Group I Metabotropic Glutamate Receptors: A Role in Neurodevelopmental Disorders?
M.V. Catania, S. D’Antoni, C.M. Bonaccorso, E. Aronica, M.F. Bear and F. Nicoletti, 2007 June. Molecular Neurobiology; 35(3):298 – 307

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